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If an embryo is not transferred in a fertility preservation cycle, a progestogen containing intrauterine device or subcutaneous, slow-release implant can be left in situ , and progesterone primed ovarian stimulation (PPOS) regimens can be utilized, thus reducing proliferation of the endometrium and endometriotic lesions

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Recent reports have found that GPX4 deletion induces iron apoptosis in M2, while M1 does not, largely because iNOS is a negative regulator of iron apoptosis and promotes M1 survival (148)